What are Phytoalexins?
Phytoalexins are bioactive molecules that have a special ability to fight off bacteria, fungus and parasites.
The phytoalexins produced by red sorghum are especially unique. A concentrated, bright red, they accumulate in certain areas of the plant, like the leaf sheath, turning the small areas of the plant bright red.
How potent is it?
It has 80 to 100 times higher antioxidant capacity than other botanical extracts!
What form does 3-Daxin come in?
3-Daxin Sorghum Bioflavonoid Complex is delivered as a water-soluble, shelf-stable, ultrafine powder.
Science
The Plant
Plants don’t have immune systems. But over millions of years, they’ve evolved to stay healthy and protect against stress and attack.
Red Sorghum – like other types of higher plants – has the ability to produce complex botanical compounds called phytoalexins that provide defense against a range of pathogens and parasites.
DISCOVERING THE PLANT'S HEALTH BENEFITS
For millennia, our ancestors collected the most intensely colored parts of the plant, using the deep red extracts for herbal teas, as preservatives, and in traditional medicine and cooking.
We’ve learned a lot about plant biochemistry since then and it turns out that the compounds that give red sorghum that intense color are bioactives responsible for keeping the plant itself healthy. And a body of research shows that these flavonoids and polyphenols have wide-ranging health and wellness benefits for us as well.
The challenge is that the plant only produces enough of these compounds to keep itself healthy – not enough to justify commercial extraction – until now.
RedLeaf was founded following the discovery of a rare natural anomaly in this defense mechanism at University of Kentucky in 2009. This natural variation causes our patented sorghum variety to produce these compounds at such high levels the plant leaves turn red to maroon. Developed over more than a decade using traditional plant breeding techniques, our sorghum varieties produce these rare, valuable phytoalexins at orders of magnitude higher than other variants. We’ve finally unlocked access to an extraordinary new extract.
Composition of the Extract
Starting with our exclusive sorghum, RedLeaf uses a proprietary extraction process to produce our Sorghum Bioflavonoid Complex extract.
Our extract is also the first commercial source of 3-deoxyanthocyanidins, a rare and ancient class of botanical polyphenol typically only found in certain flower petals and ferns.
Bioactivity
Oxidative stress, inflammation, and immunity are three fundamentally interconnected biological processes.
Our cells have developed complex and fine-tuned systems to rapidly respond to external stresses and internal failures – and just as importantly, return to homeostasis and balance.
Our sorghum extract has shown distinctive bioactivity in multiple cellular models – reducing oxidative stress and suppressing inflammatory cytokines, while activating and strengthening markers of immune health and readiness:
Potent Antioxidant
Our extract has the ability to reduce cellular oxidative stress through multiple mechanisms
• Outperforms pure reference standards of other natural bioactives, including quercetin, resveratrol, and epicatechin, in reducing oxidative stress
• Upregulates natural cellular defense pathway (Nrf2) against stress and damage
• Demonstrates unique catalase-like activity
combats inflamation
For potent suppression of cellular inflammatory cytokines – the signaling molecules that cause damaging inflammation
• Significant and dose-dependent
reduction of pro-inflammatory
cytokines in several cellular inflammation models.
SUPPORTS BALANCED IMMUNE RESPONSE
By activating and modulating molecular and cellular responses in both the innate and adaptive immune systems
• Supports increases of important signaling molecules and receptors in adaptive immune system cells
• Repolarizes innate immune system cells to active, anti-inflammatory phenotype
The science behind it
Headlines & studies:
RedLeaf’s sorghum extract drives dose-dependent increase in CD25
Inflammatory cytokine reduction in PBMCs
Flavonoid content and antioxidant capacity as compared with other botanical extracts commonly used in cosmetics
See the science behind it
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